IQSEC3P1

Across TCGA patient cohorts, IQSEC3P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,099 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible IQSEC3P1-associated GO terms across cancer lineages are Autophagosome maturation, Negative regulation of telomere capping, and Nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with IQSEC3P1 in more than 30 cancer types. Because this analysis shows association rather than direction, both IQSEC3P1-to-partner and partner-to-IQSEC3P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Autophagosome maturation grouped by IQSEC3P1-low versus IQSEC3P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQSEC3P1→partner) and Y-score (partner→IQSEC3P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Autophagosome maturation →	+0.050	+0.184	<.001	<.001	3	31
DLBC	Negative regulation of telomere capping →	+0.080	+0.235	<.001	<.001	3	30
DLBC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.068	+0.228	<.001	<.001	3	30
DLBC	Obsolete histone H3-K4 methylation →	+0.072	+0.181	<.001	.003	3	30
THYM	Obsolete regulation of histone H3-K4 methylation →	+0.069	+0.360	<.001	<.001	3	30
STAD	miRNA processing →	+0.048	+0.178	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,099 associations by consensus.

Autophagosome maturation by IQSEC3P1 expression — STAD

Explore this box plot interactively →