Across TCGA patient cohorts, IQGAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,147 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQGAP3-associated proteins across cancer lineages are KIF11_T926, LIG1, and MCM3. Each is linked with IQGAP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IQGAP3-to-partner and partner-to-IQGAP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP3→partner) and Y-score (partner→IQGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KIF11_T926 →	+1.110	+1.029	.001	.001	3	10
UCEC	LIG1 →	+0.576	+1.457	<.001	<.001	3	10
UCEC	MCM3 →	+0.812	+1.438	<.001	<.001	3	10
UCEC	MCM4 →	+0.814	+1.412	<.001	<.001	3	10
UCEC	MCM5 →	+0.782	+1.470	<.001	<.001	3	10
UCEC	MCM6 →	+0.869	+1.443	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,147 associations by consensus.

Exploration

IQGAP3 survival (RNA) · tumor vs normal (RNA) · all IQGAP3 data types