Across TCGA patient cohorts, IQGAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,861 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQGAP3-associated genes across cancer lineages are CDKN3, CENPF, and KIF14. Each is linked with IQGAP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both IQGAP3-to-partner and partner-to-IQGAP3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP3→partner) and Y-score (partner→IQGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN3 →	+0.981	+0.367	<.001	<.001	3	5
LSCC	CENPF →	+1.243	+0.644	<.001	<.001	3	5
BRCA	KIF14 →	+0.907	+0.411	<.001	<.001	3	5
UCEC	DLGAP5 →	+1.204	+0.666	.001	<.001	3	5
UCEC	CCNB1 →	+1.149	+0.675	<.001	<.001	3	5
UCEC	CDCA8 →	+1.140	+0.585	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,861 associations by consensus.

Exploration

IQGAP3 survival (RNA) · tumor vs normal (RNA) · all IQGAP3 data types