Across TCGA cell cohorts, IQGAP3 RNA expression is significantly associated with the RNA expression of many other genes, with 10,124 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IQGAP3-associated genes across cancer lineages are KIF24, ARHGAP11A, and DGCR8. Each is linked with IQGAP3 in more than 16 cancer types. Because this analysis shows association rather than direction, both IQGAP3-to-partner and partner-to-IQGAP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP3→partner) and Y-score (partner→IQGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	KIF24 →	+0.883	+1.241	<.001	<.001	3	16
BLOOD_Lymphoma	ARHGAP11A →	+1.423	+1.632	<.001	<.001	3	16
BONE	DGCR8 →	+1.125	+1.346	<.001	<.001	3	16
SKIN	MXD3 →	+1.809	+1.423	<.001	<.001	3	15
BONE	KIFC1 →	+1.332	+1.773	.006	<.001	3	15
SOFT_TISSUE	GEN1 →	+1.151	+1.446	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,124 associations by consensus.

Exploration

IQGAP3 survival (RNA) · tumor vs normal (RNA) · all IQGAP3 data types