IQGAP3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IQGAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,635 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible IQGAP3-associated GO terms across cancer lineages are Assembly of actomyosin apparatus involved in mitotic cytokinesis, Mitotic actomyosin contractile ring assembly, and Mitotic actomyosin contractile ring assembly actin filament organization. Each is linked with IQGAP3 in more than 17 cancer types. Because this analysis shows association rather than direction, both IQGAP3-to-partner and partner-to-IQGAP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP3→partner) and Y-score (partner→IQGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEAssembly of actomyosin apparatus involved in mitotic cytokinesis →+0.266+1.590<.001<.001318
BONEMitotic actomyosin contractile ring assembly →+0.266+1.590<.001<.001318
BONEMitotic actomyosin contractile ring assembly actin filament organization →+0.266+1.590<.001<.001318
BONEActomyosin contractile ring assembly actin filament organization →+0.294+1.592<.001<.001318
BONEAssembly of actomyosin apparatus involved in cytokinesis →+0.207+1.518<.001<.001318
BONEActomyosin contractile ring assembly →+0.207+1.518<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

Exploration