IQGAP1

Across TCGA patient cohorts, IQGAP1 RNA expression is significantly associated with the RNA expression of many other genes, with 20,052 significant associations in total. ACC shows the largest number of these associations.

The most reproducible IQGAP1-associated genes across cancer lineages are CTTNBP2NL, FBXO28, and ASXL2. Each is linked with IQGAP1 in more than 33 cancer types. Because this analysis shows association rather than direction, both IQGAP1-to-partner and partner-to-IQGAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQGAP1 versus CTTNBP2NL in CHOL, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQGAP1→partner) and Y-score (partner→IQGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	CTTNBP2NL →	+1.608	+1.900	.001	<.001	3	34
UVM	FBXO28 →	+1.264	+1.905	<.001	<.001	3	34
CHOL	ASXL2 →	+1.443	+1.956	<.001	<.001	3	34
DLBC	SPOPL →	+1.463	+1.527	<.001	<.001	3	34
DLBC	TMF1 →	+1.497	+1.573	<.001	<.001	3	34
DLBC	SEC24D →	+1.660	+1.436	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,052 associations by consensus.

IQGAP1 vs CTTNBP2NL — CHOL

Explore this scatter interactively →