IQCM

Across TCGA cell cohorts, IQCM RNA expression is significantly associated with the RNA expression of many other genes, with 1,130 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible IQCM-associated genes across cancer lineages are H2BW1, DEFB126, and OR52L1. Each is linked with IQCM in more than 3 cancer types. Because this analysis shows association rather than direction, both IQCM-to-partner and partner-to-IQCM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCM versus H2BW1 in PANCREAS, with a Pearson correlation of 0.86.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCM→partner) and Y-score (partner→IQCM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	H2BW1 →	+0.426	+0.060	<.001	.008	3	4
BLOOD_Lymphoma	DEFB126 →	+0.249	+0.073	<.001	<.001	3	4
BLOOD_Lymphoma	OR52L1 →	+0.056	+0.062	<.001	<.001	3	3
OESOPHAGUS	TAS2R38 →	+0.720	+0.322	.001	.002	2	3
BLOOD_Lymphoma	OR52E5 →	+0.047	+0.115	<.001	<.001	3	2
SOFT_TISSUE	CCDC179 →	+0.082	+0.033	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,130 associations by consensus.

IQCM vs H2BW1 — PANCREAS

Explore this scatter interactively →