IQCK

Across TCGA patient cohorts, IQCK RNA expression is significantly associated with the protein abundance of many other proteins, with 13,961 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IQCK-associated proteins across cancer lineages are IFT140, IFT46, and THUMPD1. Each is linked with IQCK in more than 6 cancer types. Because this analysis shows association rather than direction, both IQCK-to-partner and partner-to-IQCK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCK versus IFT140 in BRCA, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCK→partner) and Y-score (partner→IQCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IFT140 →	+0.577	+0.907	<.001	<.001	3	7
OV	IFT46 →	+0.641	+0.746	<.001	.001	3	7
BRCA	THUMPD1 →	+0.407	+0.811	<.001	<.001	3	7
BRCA	WDR19 →	+0.450	+0.898	<.001	<.001	3	7
COAD	WDR35 →	+1.981	+0.728	.004	.005	3	7
BRCA	IFT122 →	+0.370	+0.862	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,961 associations by consensus.

IQCK vs IFT140 — BRCA

Explore this scatter interactively →