IQCK

Across TCGA cell cohorts, IQCK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,389 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IQCK-associated GO terms across cancer lineages are Intraciliary anterograde transport, Protein localization to cilium, and Transport along microtubule. Each is linked with IQCK in more than 10 cancer types. Because this analysis shows association rather than direction, both IQCK-to-partner and partner-to-IQCK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by IQCK-low versus IQCK-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCK→partner) and Y-score (partner→IQCK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Intraciliary anterograde transport →	+0.112	+0.948	<.001	.001	3	11
BLOOD_Myeloma	Protein localization to cilium →	+0.053	+1.351	.002	.001	3	11
LUNG_SCLC	Transport along microtubule →	+0.079	+1.162	<.001	<.001	3	10
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.084	+1.429	<.001	<.001	3	10
BREAST	Microtubule-based transport →	+0.053	+1.146	<.001	<.001	3	9
CNS	Protein localization to ciliary transition zone →	+0.055	+1.028	.003	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,389 associations by consensus.

Intraciliary anterograde transport by IQCK expression — LUNG_SCLC

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