Across TCGA patient cohorts, IQCJ RNA expression is significantly associated with the protein abundance of many other proteins, with 10,917 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IQCJ-associated proteins across cancer lineages are RPL10, RPS2, and SEPTIN4. Each is linked with IQCJ in more than 2 cancer types. Because this analysis shows association rather than direction, both IQCJ-to-partner and partner-to-IQCJ results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCJ→partner) and Y-score (partner→IQCJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL10 →	-0.307	-0.223	<.001	.003	3	3
BRCA	RPS2 →	-0.240	-0.218	<.001	<.001	3	3
GBM	SEPTIN4 →	+0.768	+0.476	<.001	<.001	3	3
GBM	LHPP →	+0.389	+0.456	<.001	<.001	3	3
HNSC	PRKAB2 →	+0.422	+0.255	<.001	.002	3	3
GBM	SRRM1_T614 →	-0.335	-0.559	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,917 associations by consensus.

Exploration

IQCJ survival (RNA) · tumor vs normal (RNA) · all IQCJ data types