Across TCGA pan-cancer cohorts, IQCJ RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of IQCJ’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where IQCJ RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IQCJ is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

LUAD, LUSC, and KIRC are the cancer types where IQCJ tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IQCJ RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.029	.004	4	view →
LUSC	Male	All	+0.033	.006	3	view →
KIRC	Female	All	−0.011	.012	2	view →
STAD	Male	All	+0.012	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: IQCJ RNA expression & survival · all IQCJ data types