Across TCGA patient cohorts, IQCJ mutation is significantly associated with the RNA expression of many other genes, with 171 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IQCJ-associated genes across cancer lineages are RNU6-236P, RNU6-819P, and NATP. Each is linked with IQCJ in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCJ-to-partner and partner-to-IQCJ results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCJ→partner) and Y-score (partner→IQCJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-236P →	+0.324	+3.656	<.001	.006	3	2
LUAD	RNU6-819P →	+0.404	+4.341	.002	<.001	3	2
LUAD	NATP →	+0.099	+3.658	.003	.003	3	2
UCEC	RPS10-NUDT3 →	+0.382	+2.724	<.001	.007	3	1
UCEC	H2BC14 →	+0.574	+3.595	.002	.001	3	1
UCEC	MIR6859-2 →	+0.437	+2.427	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 171 associations by consensus.

Exploration

IQCJ survival (RNA) · tumor vs normal (RNA) · all IQCJ data types