IQCH

Across TCGA cell cohorts, IQCH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,692 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IQCH-associated GO terms across cancer lineages are Sperm motility, Intraciliary anterograde transport, and Flagellated sperm motility. Each is linked with IQCH in more than 11 cancer types. Because this analysis shows association rather than direction, both IQCH-to-partner and partner-to-IQCH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by IQCH-low versus IQCH-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCH→partner) and Y-score (partner→IQCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Sperm motility →	-0.088	-0.576	.003	.002	3	12
CNS	Intraciliary anterograde transport →	+0.080	+0.424	<.001	<.001	3	12
URINARY_TRACT	Flagellated sperm motility →	-0.088	-0.576	.003	.002	3	12
URINARY_TRACT	Cilium movement involved in cell motility →	-0.076	-0.509	.006	.008	3	10
LIVER	Protein localization to cilium →	+0.068	+0.386	<.001	<.001	3	10
CNS	Vesicle-mediated transport to the plasma membrane →	+0.050	+0.573	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,692 associations by consensus.

Sperm motility by IQCH expression — URINARY_TRACT

Explore this box plot interactively →