IQCE

Across TCGA patient cohorts, IQCE protein abundance is significantly associated with the RNA expression of many other genes, with 2,917 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IQCE-associated genes across cancer lineages are TATDN2P1, FAM242C, and GINS1. Each is linked with IQCE in more than 1 cancer types. Because this analysis shows association rather than direction, both IQCE-to-partner and partner-to-IQCE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCE versus TATDN2P1 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCE→partner) and Y-score (partner→IQCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TATDN2P1 →	+0.690	+0.541	.009	<.001	3	2
OV	FAM242C →	+0.343	+1.548	.003	.002	3	2
LSCC	GINS1 →	-0.807	-0.793	<.001	.003	3	2
UCEC	GIPR →	+0.861	+0.347	.001	.005	3	2
UCEC	SPAG1 →	+0.981	+0.459	<.001	<.001	3	2
UCEC	STX2 →	+0.757	+0.281	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,917 associations by consensus.

IQCE vs TATDN2P1 — UCEC

Explore this scatter interactively →