family with sequence similarity 242 member CGenealiases: []
Q-omics provides the consensus-scored FAM242C profile across patient tissues and cancer cell-line models. FAM242C expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, FAM242C is differentially expressed in 15, with the highest sampling consensus in KIRC. Additionally, FAM242C RNA expression shows 13,962 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UCEC, KIRC, and UVM as cancer lineages where FAM242C shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAM242C — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAM242C survival associations across molecular data types. FAM242C RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAM242C RNA expression–survival associations across cancer types. High FAM242C expression shows unfavorable associations in UCEC, THCA, STAD, LGG and CHOL, but favorable associations in BLCA. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for FAM242C RNA expression.
This table summarizes FAM242C tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for FAM242C. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAM242C shows lower tumor expression in KIRC, KIRP, KICH and UCEC and higher tumor expression in LUSC and BRCA. The KIRC box plot shows higher FAM242C RNA expression in normal versus tumor tissue (log2 FC = −1.333, t-test p < 0.001).
This table shows molecular features associated with FAM242C in patient tissues and cancer cell lines. In patient samples, FAM242C shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
