FAM242C

Across TCGA pan-cancer cohorts, FAM242C RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FAM242C data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM242C RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM242C expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRP show a favorable association.

UCEC, THCA, and STAD are the cancer types where FAM242C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.547	0.755	<.001	96	view →
THCA	OS	Median	II,III,IV	0.958	0.993	.003	72	view →
STAD	DFS	Quartile	All	0.515	0.687	.004	56	view →
LGG	DFS	Median	All	0.287	0.496	<.001	51	view →
BLCA	OS	Median	All	0.505	0.366	.006	27	view →
CHOL	OS	Tertile	All	0.462	1.000	.002	22	view →
KIRC	DFS	Tertile	All	0.509	0.681	.004	18	view →
KIRP	DFS	Median	All	0.972	0.809	.012	18	view →
PRAD	DFS	Tertile	All	0.679	0.842	<.001	18	view →
LIHC	OS	Median	III,IV	0.424	0.778	<.001	14	view →
LUAD	DFS	Median	III,IV	0.333	0.621	.008	14	view →
LUSC	DFS	Median	II,III,IV	0.533	0.679	.005	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FAM242C–UCEC (DFS)

Open the UCEC breakdown →