IQCD

Across TCGA patient cohorts, IQCD RNA expression is significantly associated with the protein abundance of many other proteins, with 11,889 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IQCD-associated proteins across cancer lineages are WDR19, WDR35, and WDR54. Each is linked with IQCD in more than 5 cancer types. Because this analysis shows association rather than direction, both IQCD-to-partner and partner-to-IQCD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCD versus WDR19 in BRCA, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCD→partner) and Y-score (partner→IQCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR19 →	+0.368	+0.688	<.001	<.001	3	6
UCEC	WDR35 →	+0.328	+0.699	<.001	.002	3	5
OV	WDR54 →	+0.424	+0.693	.003	.002	3	5
PDAC	IFT43 →	+0.413	+0.389	<.001	.004	3	5
UCEC	TTC21B →	+0.257	+0.904	.002	.001	3	5
GBM	TTC25_S542 →	+1.072	+0.696	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,889 associations by consensus.

IQCD vs WDR19 — BRCA

Explore this scatter interactively →