IQCB1

Across TCGA pan-cancer cohorts, IQCB1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated IQCB1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IQCB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated IQCB1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, PDAC, and LSCC are the cancer types where IQCB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.900	0.427	.013	10	view →
PDAC	OS	Median	III,IV	0.241	0.835	.038	6	view →
LSCC	DFS	Quartile	All	1.000	0.349	.026	5	view →
OV	DFS	Median	All	1.000	0.639	.038	4	view →
CCRCC	OS	Quartile	III,IV	0.349	0.853	.028	4	view →
LUAD	OS	Median	II,III,IV	0.728	0.322	.037	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

IQCB1–UCEC (DFS)

Open the UCEC breakdown →