IQCB1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IQCB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,851 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IQCB1-associated proteins across cancer lineages are UMPS, HMCES, and MCM2. Each is linked with IQCB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IQCB1-to-partner and partner-to-IQCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IQCB1 versus UMPS in LSCC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCB1→partner) and Y-score (partner→IQCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCUMPS →+0.401+0.672<.001<.00138
LSCCHMCES →+0.529+0.731<.001<.00137
GBMMCM2 →+0.845+0.370<.001.00137
GBMPRPF4 →+0.326+0.341<.001.00236
GBMSF3B6 →+0.314+0.392<.001.00136
GBMCHERP →+0.295+0.444<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,851 associations by consensus.

IQCB1 vs UMPS — LSCC

Per-sample scatter of IQCB1 vs UMPS in LSCC (Pearson r = 0.66).

Explore this scatter interactively →

Exploration