IQCB1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IQCB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,551 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IQCB1-associated GO terms across cancer lineages are Recombinational repair, DNA-templated DNA replication maintenance of fidelity, and Double-strand break repair via homologous recombination. Each is linked with IQCB1 in more than 16 cancer types. Because this analysis shows association rather than direction, both IQCB1-to-partner and partner-to-IQCB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Recombinational repair grouped by IQCB1-low versus IQCB1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IQCB1→partner) and Y-score (partner→IQCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONERecombinational repair →+0.107+1.081.001.001317
UPPER_AERODIGESTIVE_TRACTDNA-templated DNA replication maintenance of fidelity →+0.123+1.011<.001<.001316
BONEDouble-strand break repair via homologous recombination →+0.091+0.891.001.001316
BONEReplication fork processing →+0.148+1.113.001<.001315
SOFT_TISSUERegulation of RNA stability →+0.069+0.900<.001<.001315
SOFT_TISSUEMitotic G2/M transition checkpoint →+0.111+0.941<.001<.001315
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,551 associations by consensus.

Recombinational repair by IQCB1 expression — BONE

Box plot of Recombinational repair in IQCB1-low vs IQCB1-high samples in BONE.

Explore this box plot interactively →

Exploration