IQCA1-AS1

Across TCGA pan-cancer cohorts, IQCA1-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated IQCA1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher IQCA1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated IQCA1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, ACC, and MESO are the cancer types where IQCA1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.917	0.830	<.001	119	view →
ACC	DFS	Tertile	All	0.258	0.615	.006	48	view →
MESO	OS	Tertile	All	0.234	0.423	.003	44	view →
UVM	DFS	Tertile	III,IV	0.290	0.681	.002	41	view →
COAD	DFS	Tertile	All	0.509	0.741	.001	36	view →
KIRP	OS	Tertile	II,III,IV	0.887	0.564	.003	34	view →
PCPG	OS	Tertile	All	0.798	0.972	.005	30	view →
OV	OS	Quartile	IV	0.198	0.443	.004	18	view →
PRAD	DFS	Tertile	All	0.816	0.910	.002	18	view →
UCEC	OS	Quartile	All	0.924	0.855	.026	10	view →
GBM	DFS	Median	All	0.270	0.164	.011	10	view →
READ	DFS	Tertile	IV	0.112	0.811	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

IQCA1-AS1–KIRC (OS)

Open the KIRC breakdown →