IQCA1-AS1

Across TCGA pan-cancer cohorts, IQCA1-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of IQCA1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IQCA1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IQCA1-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, HNSC, and KICH are the cancer types where IQCA1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IQCA1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.661	<.001	11	view →
HNSC	All	III,IV	+0.292	<.001	11	view →
KICH	All	All	−0.429	<.001	6	view →
BRCA	All	All	+0.064	.021	4	view →
COAD	All	II,III,IV	+0.088	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

IQCA1-AS1–KIRC

Open the KIRC breakdown →