IPO8

Across TCGA patient cohorts, IPO8 protein abundance is significantly associated with the RNA expression of many other genes, with 17,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO8-associated genes across cancer lineages are RAD51AP1, OIP5, and NCAPG. Each is linked with IPO8 in more than 6 cancer types. Because this analysis shows association rather than direction, both IPO8-to-partner and partner-to-IPO8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPO8 versus RAD51AP1 in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO8→partner) and Y-score (partner→IPO8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RAD51AP1 →	+1.099	+0.296	<.001	<.001	3	7
BRCA	OIP5 →	+0.701	+0.393	<.001	<.001	3	6
BRCA	NCAPG →	+1.086	+0.401	<.001	<.001	3	6
COAD	GMNN →	+0.776	+0.274	<.001	<.001	3	6
LUAD	KIF14 →	+1.066	+0.217	<.001	<.001	3	6
GBM	KIF18A →	+0.792	+0.226	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,919 associations by consensus.

IPO8 vs RAD51AP1 — LUAD

Explore this scatter interactively →