IPO5P1

Across TCGA pan-cancer cohorts, IPO5P1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated IPO5P1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IPO5P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated IPO5P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, BLCA, and PAAD are the cancer types where IPO5P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	II,III,IV	0.843	0.655	<.001	81	view →
BLCA	OS	Tertile	II,III,IV	0.699	0.504	<.001	69	view →
PAAD	OS	Median	All	0.668	0.319	<.001	53	view →
READ	DFS	Tertile	All	0.949	0.385	.003	44	view →
LUAD	OS	Quartile	All	0.761	0.592	.001	41	view →
LIHC	DFS	Quartile	II,III,IV	0.265	0.492	.001	40	view →
KIRC	OS	Tertile	All	0.689	0.551	.001	38	view →
MESO	OS	Median	All	0.723	0.299	.002	30	view →
ESCA	OS	Median	II,III,IV	0.599	0.753	.024	19	view →
ACC	OS	Median	IV	0.908	0.475	.003	18	view →
LUSC	OS	Tertile	All	0.922	0.764	.007	10	view →
KIRP	DFS	Median	All	0.956	0.808	.025	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

IPO5P1–HNSC (OS)

Open the HNSC breakdown →