IPO11

Across TCGA patient cohorts, IPO11 protein abundance is significantly associated with the RNA expression of many other genes, with 16,753 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IPO11-associated genes across cancer lineages are CCNB1, CDK7, and CENPH. Each is linked with IPO11 in more than 6 cancer types. Because this analysis shows association rather than direction, both IPO11-to-partner and partner-to-IPO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPO11 versus CCNB1 in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO11→partner) and Y-score (partner→IPO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCNB1 →	+1.093	+0.358	<.001	<.001	3	7
OV	CDK7 →	+0.807	+0.388	<.001	<.001	3	7
OV	CENPH →	+0.876	+0.357	<.001	<.001	3	7
HNSC	TAF9 →	+0.653	+0.260	.002	<.001	3	6
OV	NLRP1 →	-0.736	-0.246	.009	.008	3	6
HNSC	MRPS27 →	+0.507	+0.191	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,753 associations by consensus.

IPO11 vs CCNB1 — OV

Explore this scatter interactively →