IP6K3

Across TCGA cell cohorts, IP6K3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,126 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IP6K3-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Neuroligin clustering involved in postsynaptic membrane assembly, and L-alanine transmembrane transport. Each is linked with IP6K3 in more than 6 cancer types. Because this analysis shows association rather than direction, both IP6K3-to-partner and partner-to-IP6K3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by IP6K3-low versus IP6K3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K3→partner) and Y-score (partner→IP6K3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of mRNA splicing, via spliceosome →	+0.043	+0.680	.009	.009	3	7
OVARY	Neuroligin clustering involved in postsynaptic membrane assembly →	+1.085	+0.496	<.001	.004	3	5
BONE	L-alanine transmembrane transport →	-0.203	-0.339	<.001	.009	3	5
OVARY	RNA stabilization →	+0.048	+0.369	<.001	.002	3	4
OVARY	Regulation of mRNA processing →	+0.062	+0.203	.003	.009	2	5
OVARY	Protein localization to lysosome →	+0.060	+0.412	.006	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,126 associations by consensus.

Regulation of mRNA splicing, via spliceosome by IP6K3 expression — LUNG_SCLC

Explore this box plot interactively →