IP6K2

Across TCGA patient cohorts, IP6K2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,004 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IP6K2-associated proteins across cancer lineages are SETD2, TOP2B, and QRICH1. Each is linked with IP6K2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IP6K2-to-partner and partner-to-IP6K2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IP6K2 versus SETD2 in GBM, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K2→partner) and Y-score (partner→IP6K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SETD2 →	+0.288	+0.407	<.001	<.001	3	7
GBM	TOP2B →	+0.468	+0.441	<.001	<.001	3	7
OV	QRICH1 →	+0.265	+0.551	<.001	<.001	3	7
OV	RBM15B →	+0.302	+0.440	<.001	<.001	3	7
LSCC	SMARCC1 →	+0.349	+0.194	<.001	.006	3	6
LSCC	ADNP →	+0.421	+0.438	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,004 associations by consensus.

IP6K2 vs SETD2 — GBM

Explore this scatter interactively →