IP6K2

Across TCGA cell cohorts, IP6K2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,808 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IP6K2-associated GO terms across cancer lineages are Response to flavonoid, Positive regulation of DNA repair, and Positive regulation of DNA metabolic process. Each is linked with IP6K2 in more than 19 cancer types. Because this analysis shows association rather than direction, both IP6K2-to-partner and partner-to-IP6K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to flavonoid grouped by IP6K2-low versus IP6K2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K2→partner) and Y-score (partner→IP6K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to flavonoid →	+0.208	+0.992	<.001	<.001	3	20
BONE	Positive regulation of DNA repair →	+0.063	+0.555	.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA metabolic process →	+0.063	+1.127	<.001	<.001	3	14
LUNG_SCLC	Regulation of DNA repair →	+0.049	+0.516	<.001	<.001	3	14
BREAST	Regulation of double-strand break repair →	+0.057	+0.795	.006	.006	3	14
BONE	Positive regulation of DNA recombination →	+0.107	+0.779	.002	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,808 associations by consensus.

Response to flavonoid by IP6K2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →