IP6K2

Across TCGA cell cohorts, IP6K2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IP6K2-associated genes across cancer lineages are GPR171 and CCL18. Each is linked with IP6K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IP6K2-to-partner and partner-to-IP6K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR171 grouped by IP6K2-low versus IP6K2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K2→partner) and Y-score (partner→IP6K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GPR171 →	+0.019	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GPR171 by IP6K2 expression — LARGE_INTESTINE

Explore this box plot interactively →