INVS

Across TCGA patient cohorts, INVS RNA expression is significantly associated with the protein abundance of many other proteins, with 15,053 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INVS-associated proteins across cancer lineages are SPIN1, TEX10, and FUBP3. Each is linked with INVS in more than 5 cancer types. Because this analysis shows association rather than direction, both INVS-to-partner and partner-to-INVS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INVS versus SPIN1 in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INVS→partner) and Y-score (partner→INVS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPIN1 →	+0.417	+0.272	<.001	<.001	3	6
LSCC	TEX10 →	+0.241	+0.442	<.001	<.001	3	5
GBM	FUBP3 →	+0.207	+0.280	<.001	<.001	3	5
GBM	WDR5 →	+0.341	+0.304	<.001	<.001	3	5
GBM	SEC23IP →	-0.287	-0.331	<.001	<.001	3	4
GBM	MTA1 →	+0.392	+0.332	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,053 associations by consensus.

INVS vs SPIN1 — GBM

Explore this scatter interactively →