INVS

Across TCGA cell cohorts, INVS RNA expression is significantly associated with the go_rna of many other GO terms, with 4,554 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INVS-associated GO terms across cancer lineages are mRNA export from nucleus, Nucleic acid transport, and RNA transport. Each is linked with INVS in more than 17 cancer types. Because this analysis shows association rather than direction, both INVS-to-partner and partner-to-INVS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by INVS-low versus INVS-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INVS→partner) and Y-score (partner→INVS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA export from nucleus →	+0.122	+0.999	.001	.001	3	18
OESOPHAGUS	Nucleic acid transport →	+0.110	+0.922	.001	.002	3	17
OESOPHAGUS	RNA transport →	+0.110	+0.922	.001	.002	3	17
OESOPHAGUS	Establishment of RNA localization →	+0.106	+0.893	.001	.003	3	17
OESOPHAGUS	RNA localization →	+0.100	+0.877	.001	.003	3	17
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.123	+1.104	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,554 associations by consensus.

mRNA export from nucleus by INVS expression — OESOPHAGUS

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