INTU

Across TCGA cell cohorts, INTU RNA expression is significantly associated with the go_rna of many other GO terms, with 3,864 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INTU-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Regulation of myoblast fusion, and Negative regulation of myoblast fusion. Each is linked with INTU in more than 13 cancer types. Because this analysis shows association rather than direction, both INTU-to-partner and partner-to-INTU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by INTU-low versus INTU-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTU→partner) and Y-score (partner→INTU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.118	+0.804	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.132	+0.811	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.131	+0.620	<.001	.007	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.126	+0.620	<.001	.007	3	13
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.071	+0.899	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.109	+0.947	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,864 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by INTU expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →