INTU

Across TCGA pan-cancer cohorts, INTU RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of INTU’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where INTU RNA is more highly expressed in tumor relative to normal tissue. In most cancer types INTU is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

LIHC, KICH, and BRCA are the cancer types where INTU tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INTU RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	+0.354	<.001	7	view →
KICH	Female	All	−0.728	<.001	6	view →
BRCA	Female	All	−0.479	<.001	6	view →
CHOL	Female	All	+1.556	<.001	5	view →
THCA	All	All	−0.408	<.001	5	view →
COAD	All	All	+0.235	.009	4	view →
HNSC	All	II,III,IV	+0.227	.034	3	view →
KIRC	All	All	+0.222	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

INTU–LIHC

Open the LIHC breakdown →