INTS8

Across TCGA patient cohorts, INTS8 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,020 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS8-associated proteins across cancer lineages are MBD3, RBM12B, and STK3. Each is linked with INTS8 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS8-to-partner and partner-to-INTS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS8 versus MBD3 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS8→partner) and Y-score (partner→INTS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MBD3 →	+0.532	+0.498	<.001	<.001	3	6
GBM	RBM12B →	+0.262	+0.316	<.001	<.001	3	6
OV	STK3 →	+0.415	+0.648	<.001	<.001	3	6
LUAD	YTHDF3 →	+0.290	+0.485	<.001	<.001	3	6
BRCA	OTUD6B →	+0.474	+0.585	<.001	<.001	3	6
UCEC	SCRIB →	+0.291	+0.395	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,020 associations by consensus.

INTS8 vs MBD3 — LSCC

Explore this scatter interactively →