INTS8

Across TCGA patient cohorts, INTS8 protein abundance is significantly associated with the RNA expression of many other genes, with 12,567 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS8-associated genes across cancer lineages are EIF3B, CKAP2, and NCAPH. Each is linked with INTS8 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS8-to-partner and partner-to-INTS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS8 versus EIF3B in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS8→partner) and Y-score (partner→INTS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF3B →	+0.519	+0.176	<.001	<.001	3	6
OV	CKAP2 →	+0.757	+0.196	.002	.003	3	6
BRCA	NCAPH →	+0.813	+0.212	<.001	<.001	3	6
BRCA	CCNB1 →	+0.800	+0.161	.001	.003	3	6
BRCA	KIF2C →	+1.193	+0.185	<.001	.001	3	6
HNSC	SKA1 →	+1.100	+0.247	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,567 associations by consensus.

INTS8 vs EIF3B — BRCA

Explore this scatter interactively →