INTS8

Across TCGA cell cohorts, INTS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,771 significant associations in total. BONE shows the largest number of these associations.

The most reproducible INTS8-associated GO terms across cancer lineages are Blastocyst growth, Mismatch repair, and Regulation of centrosome duplication. Each is linked with INTS8 in more than 11 cancer types. Because this analysis shows association rather than direction, both INTS8-to-partner and partner-to-INTS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Blastocyst growth grouped by INTS8-low versus INTS8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS8→partner) and Y-score (partner→INTS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Blastocyst growth →	+0.209	+1.327	<.001	<.001	3	12
BLOOD_Lymphoma	Mismatch repair →	+0.060	+0.740	.002	.004	3	11
LUNG_SCLC	Regulation of centrosome duplication →	+0.082	+0.656	<.001	<.001	3	10
OVARY	snRNA metabolic process →	+0.054	+0.640	.002	.006	3	10
BONE	Regulation of mononuclear cell proliferation →	-0.083	-1.356	<.001	<.001	3	10
LUNG_SCLC	Regulation of maintenance of sister chromatid cohesion →	+0.135	+0.901	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,771 associations by consensus.

Blastocyst growth by INTS8 expression — LIVER

Explore this box plot interactively →