INTS7

Across TCGA cell cohorts, INTS7 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible INTS7-associated genes across cancer lineages are SPATA48, GJA8, and IL22. Each is linked with INTS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS7-to-partner and partner-to-INTS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA48 grouped by INTS7-low versus INTS7-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS7→partner) and Y-score (partner→INTS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPATA48 →	+0.009	+4.662	<.001	.005	3	2
STOMACH	GJA8 →	+0.015	+4.285	<.001	.007	3	1
STOMACH	IL22 →	+0.035	+4.285	<.001	.007	3	1
STOMACH	MAS1 →	+0.005	+4.285	<.001	.007	3	1
STOMACH	LRRC72 →	+0.070	+4.285	<.001	.007	3	1
STOMACH	KRTAP10-5 →	+0.027	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

SPATA48 by INTS7 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →