Across TCGA patient cohorts, INTS5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,386 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS5-associated genes across cancer lineages are SNRPE, BLM, and BIN2. Each is linked with INTS5 in more than 4 cancer types. Because this analysis shows association rather than direction, both INTS5-to-partner and partner-to-INTS5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS5→partner) and Y-score (partner→INTS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPE →	+0.657	+0.104	.005	.005	3	5
LSCC	BLM →	+0.707	+0.171	.001	.003	3	5
HNSC	BIN2 →	-0.810	-0.139	<.001	.002	3	5
OV	AIF1 →	-1.107	-0.333	<.001	<.001	3	5
OV	CORO1A →	-0.935	-0.230	.002	.001	2	5
OV	TRBC1 →	-1.795	-0.257	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,386 associations by consensus.

Exploration

INTS5 survival (RNA) · tumor vs normal (RNA) · all INTS5 data types