INTS4P2

Across TCGA patient cohorts, INTS4P2 mutation is significantly associated with the RNA expression of many other genes, with 662 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INTS4P2-associated genes across cancer lineages are SNORA10B, OR6C1, and RNU4-58P. Each is linked with INTS4P2 in more than 2 cancer types. Because this analysis shows association rather than direction, both INTS4P2-to-partner and partner-to-INTS4P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA10B grouped by INTS4P2-low versus INTS4P2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS4P2→partner) and Y-score (partner→INTS4P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORA10B →	+0.357	+5.441	<.001	.005	3	3
SKCM	OR6C1 →	+0.187	+3.623	<.001	.006	3	2
UCEC	RNU4-58P →	+0.274	+3.133	<.001	.002	3	2
UCEC	RNA5SP458 →	+0.219	+3.109	.001	.007	3	2
BRCA	MIR6131 →	+0.351	+5.317	<.001	.006	3	1
SKCM	AQP12B →	+0.059	+3.265	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 662 associations by consensus.

SNORA10B by INTS4P2 expression — BRCA

Explore this box plot interactively →