INTS2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INTS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,897 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS2-associated proteins across cancer lineages are COIL, TLK2, and SUPT6H. Each is linked with INTS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both INTS2-to-partner and partner-to-INTS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS2 versus COIL in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS2→partner) and Y-score (partner→INTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACOIL →+0.507+0.643<.001.00137
OVTLK2 →+0.473+0.639<.001.00137
LSCCSUPT6H →+0.321+0.675<.001<.00136
PDACDCAF7 →+0.364+0.412<.001<.00136
GBMDDX42 →+0.342+0.401<.001<.00136
LSCCRECQL5 →+0.355+0.475<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,897 associations by consensus.

INTS2 vs COIL — BRCA

Per-sample scatter of INTS2 vs COIL in BRCA (Pearson r = 0.35).

Explore this scatter interactively →

Exploration