INTS2

Across TCGA patient cohorts, INTS2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,190 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS2-associated genes across cancer lineages are CENPA, CKAP2, and NUF2. Each is linked with INTS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS2-to-partner and partner-to-INTS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS2 versus CENPA in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS2→partner) and Y-score (partner→INTS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CENPA →	+1.130	+0.254	<.001	<.001	3	6
OV	CKAP2 →	+0.763	+0.230	<.001	<.001	3	6
LSCC	NUF2 →	+1.139	+0.240	<.001	<.001	3	6
HNSC	MRPL9 →	+0.706	+0.169	.004	<.001	3	6
HNSC	RAE1 →	+0.680	+0.167	.009	.003	3	6
HNSC	UCK2 →	+0.733	+0.226	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,190 associations by consensus.

INTS2 vs CENPA — HNSC

Explore this scatter interactively →