INTS13

Across TCGA patient cohorts, INTS13 mutation is significantly associated with the RNA expression of many other genes, with 1,561 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INTS13-associated genes across cancer lineages are TXLNA, TICAM1, and AP2A2. Each is linked with INTS13 in more than 2 cancer types. Because this analysis shows association rather than direction, both INTS13-to-partner and partner-to-INTS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXLNA grouped by INTS13-low versus INTS13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS13→partner) and Y-score (partner→INTS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TXLNA →	+0.287	+2.000	.007	.003	3	3
UCEC	TICAM1 →	+0.634	+2.917	<.001	<.001	3	3
SKCM	AP2A2 →	+0.465	+3.220	.007	.009	3	2
SKCM	IRAK1 →	+0.610	+3.331	.007	.005	3	2
SKCM	SPATA12 →	+0.484	+3.195	.001	.009	3	2
SKCM	NCKIPSD →	+0.668	+3.504	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,561 associations by consensus.

TXLNA by INTS13 expression — UCEC

Explore this box plot interactively →