INTS11

Across TCGA cell cohorts, INTS11 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INTS11-associated genes across cancer lineages are OR52N5, C6orf118, and SLC6A18. Each is linked with INTS11 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS11-to-partner and partner-to-INTS11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N5 grouped by INTS11-low versus INTS11-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS11→partner) and Y-score (partner→INTS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR52N5 →	+0.013	+5.614	<.001	.002	3	1
LARGE_INTESTINE	C6orf118 →	+0.186	+3.793	<.001	.007	3	1
BLOOD_Lymphoma	SLC6A18 →	+0.027	+3.192	.003	.008	3	1
BLOOD_Lymphoma	SLC38A8 →	+0.083	+3.606	<.001	.002	3	1
BLOOD_Lymphoma	OR2L8 →	+0.020	+3.584	<.001	.004	3	1
BLOOD_Leukemia	CST2 →	+0.353	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR52N5 by INTS11 expression — PANCREAS

Explore this box plot interactively →