INTS1

Across TCGA patient cohorts, INTS1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS1-associated genes across cancer lineages are HEATR1, SNHG17, and MYBL2. Each is linked with INTS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both INTS1-to-partner and partner-to-INTS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS1 versus HEATR1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS1→partner) and Y-score (partner→INTS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HEATR1 →	+0.692	+0.191	<.001	<.001	3	7
OV	SNHG17 →	+0.590	+0.180	.008	.004	3	7
GBM	MYBL2 →	+0.979	+0.203	<.001	<.001	3	6
OV	EBPL →	+0.811	+0.193	<.001	.002	3	6
HNSC	SRSF6 →	+0.665	+0.216	<.001	<.001	3	6
HNSC	POLR1B →	+0.567	+0.137	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,313 associations by consensus.

INTS1 vs HEATR1 — HNSC

Explore this scatter interactively →