Across TCGA patient cohorts, INSYN2A RNA expression is significantly associated with the protein abundance of many other proteins, with 15,871 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible INSYN2A-associated proteins across cancer lineages are TRIM28, GMIP, and PTPN6. Each is linked with INSYN2A in more than 5 cancer types. Because this analysis shows association rather than direction, both INSYN2A-to-partner and partner-to-INSYN2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2A→partner) and Y-score (partner→INSYN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.439	+0.984	<.001	.001	3	6
GBM	GMIP →	-0.384	-1.212	<.001	<.001	3	6
GBM	PTPN6 →	-0.595	-0.939	<.001	.006	3	5
BRCA	PTPN7 →	-0.508	-1.429	<.001	<.001	3	5
HNSC	HDAC2 →	+0.249	+0.587	.003	.001	3	5
BRCA	THEMIS2 →	-0.494	-1.788	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,871 associations by consensus.

Exploration

INSYN2A survival (RNA) · tumor vs normal (RNA) · all INSYN2A data types