Across TCGA patient cohorts, INSYN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,568 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INSYN1-associated proteins across cancer lineages are TLN2, HDGFL3, and PURA. Each is linked with INSYN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both INSYN1-to-partner and partner-to-INSYN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN1→partner) and Y-score (partner→INSYN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TLN2 →	+0.442	+0.380	<.001	<.001	3	7
BRCA	HDGFL3 →	+0.822	+1.240	<.001	<.001	3	7
BRCA	PURA →	+0.552	+1.264	<.001	<.001	3	6
COAD	SEPTIN7 →	+0.263	+0.362	<.001	<.001	3	6
LUAD	DDX21_S89 →	-1.092	-0.548	<.001	<.001	2	7
GBM	STXBP1 →	+0.756	+1.114	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,568 associations by consensus.

Exploration

INSYN1 survival (RNA) · tumor vs normal (RNA) · all INSYN1 data types