INSR

Across TCGA patient cohorts, INSR RNA expression is significantly associated with the protein abundance of many other proteins, with 13,811 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible INSR-associated proteins across cancer lineages are SVIL_T852, PRELP, and UPP1. Each is linked with INSR in more than 4 cancer types. Because this analysis shows association rather than direction, both INSR-to-partner and partner-to-INSR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSR versus SVIL_T852 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSR→partner) and Y-score (partner→INSR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SVIL_T852 →	+1.088	+0.673	<.001	.001	3	5
OV	PRELP →	+0.932	+1.036	.001	<.001	3	5
HNSC	UPP1 →	-0.569	-0.582	.002	.001	3	5
HNSC	RANGAP1 →	-0.272	-0.432	.001	.008	3	5
HNSC	N4BP1 →	-0.274	-0.569	<.001	<.001	3	5
BRCA	EIF4G1 →	-0.284	-0.826	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,811 associations by consensus.

INSR vs SVIL_T852 — OV

Explore this scatter interactively →