INSM1

Across TCGA patient cohorts, INSM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,098 significant associations in total. THCA shows the largest number of these associations.

The most reproducible INSM1-associated GO terms across cancer lineages are Maintenance of cell number, Protein localization to microtubule organizing center, and Positive regulation of double-strand break repair. Each is linked with INSM1 in more than 16 cancer types. Because this analysis shows association rather than direction, both INSM1-to-partner and partner-to-INSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of cell number grouped by INSM1-low versus INSM1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM1→partner) and Y-score (partner→INSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Maintenance of cell number →	+0.069	+0.897	.002	<.001	2	17
GBM	Protein localization to microtubule organizing center →	+0.040	+1.319	<.001	<.001	3	15
SCLC	Positive regulation of double-strand break repair →	+0.076	+1.290	<.001	.004	1	17
GBM	Negative regulation of chromosome organization →	+0.035	+0.991	<.001	<.001	3	14
TGCT	Cell cycle G1/S phase transition →	+0.027	+0.905	<.001	<.001	3	14
GBM	Negative regulation of mitotic cell cycle →	+0.041	+1.456	<.001	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,098 associations by consensus.

Maintenance of cell number by INSM1 expression — DLBC

Explore this box plot interactively →