INSM1

Across TCGA patient cohorts, INSM1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,839 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible INSM1-associated genes across cancer lineages are PPIP5K2, ITPR1, and CEP120. Each is linked with INSM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INSM1-to-partner and partner-to-INSM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSM1 versus PPIP5K2 in HNSC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM1→partner) and Y-score (partner→INSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPIP5K2 →	+0.958	+2.451	<.001	.007	3	2
BRCA	ITPR1 →	+1.226	+1.004	<.001	<.001	3	2
HNSC	CEP120 →	+0.902	+2.451	<.001	.007	3	2
HNSC	DMXL1 →	+0.468	+1.204	<.001	.001	3	2
HNSC	RN7SL455P →	+0.711	+1.854	.001	.005	3	2
BRCA	ZNF207 →	+0.691	+1.145	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,839 associations by consensus.

INSM1 vs PPIP5K2 — HNSC

Explore this scatter interactively →