INSM1

Across TCGA patient cohorts, INSM1 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,536 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible INSM1-associated proteins across cancer lineages are SEPTIN2_S218, RCN3, and RELL1. Each is linked with INSM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INSM1-to-partner and partner-to-INSM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSM1 versus SEPTIN2_S218 in BRCA, with a Pearson correlation of -0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM1→partner) and Y-score (partner→INSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN2_S218 →	-0.564	-1.197	.002	.002	3	2
BRCA	RCN3 →	-0.690	-1.129	<.001	<.001	3	1
BRCA	RELL1 →	+0.995	+1.599	<.001	<.001	3	1
BRCA	RERE_S1266 →	+0.746	+1.742	.001	<.001	3	1
BRCA	RNF123 →	+0.569	+1.615	<.001	<.001	3	1
BRCA	RNF139 →	+0.502	+1.747	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,536 associations by consensus.

INSM1 vs SEPTIN2_S218 — BRCA

Explore this scatter interactively →